HPLC Column, IEX WCX, 10um, 4.0mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent IEX WCX is a weak cation exchange (WCX) HPLC stationary phase manufactured using high-purity silica and carboxylic acid functional groups that provide pH-dependent negative charge characteristics. This weak cation exchange mechanism offers selective retention and separation of positively charged analytes while allowing greater control of retention through mobile phase pH adjustments. The stationary phase is particularly useful for basic compounds, amines, peptides, and other cationic species and serves as an excellent alternative for USP L9 methods requiring weak cation exchange selectivity.
67091-25P-4 is a 250 mm x 4.0 mm ID analytical column packed with 10 µm WCX particles with a 100 Å pore size. The extended 250 mm length provides increased theoretical plate counts and maximum resolving power for complex ion exchange separations, impurity profiling, purification studies, and challenging analytical applications requiring enhanced separation of closely related cationic compounds. The 10 µm particle size provides low backpressure and supports higher flow rates than smaller particle packings. The 4.0 mm ID format is commonly selected for legacy methods and typically operates at approximately 0.8–2.5 mL/min on conventional HPLC systems.
This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other cationic species. The weak cation exchange functionality allows chromatographers to optimize selectivity through pH control while maintaining excellent efficiency and reproducibility. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
Weak cation exchange (WCX) stationary phase
Carboxylic acid functional groups
pH-dependent retention characteristics
Suitable alternative for USP L9 methods
10 µm particles for lower backpressure
Supports higher flow rates
Maximum resolving power from 250 mm column length
High-purity silica support
Typical Applications
USP L9 methods
Ion exchange chromatography
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Impurity profiling
Purification studies
Specifications
Product Type: HPLC Column
Stationary Phase: IEX WCX
USP Classification: L9
Chromatography Mode: Weak Cation Exchange
Functional Group: Carboxylic Acid
Functional pH Range: Approximately pH 2.5–7
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Recommended Flow Rate: 0.8–2.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for ion exchange chromatography
Retains positively charged analytes
Retention can be adjusted through mobile phase pH control
Longer column length provides maximum chromatographic resolution
Lower backpressure compared to smaller particle columns
Supports higher flow rates for routine and preparative methods
Excellent alternative for many USP L9 methods
Special Order Item